Chronic kidney disease and the skeleton

Pathogenesis, complications and principles of management

Authors

  • B Thibedi
  • EJ Raubenheimer
  • CEE Noffke

Keywords:

uraemic osteodystrophy, osteitis fibrosa, hyperparathyroidism, renal failure, osteomalacia

Abstract

Skeletal and extra-skeletal changes in chronic kidney disease are the result of deteriorating mineral homeostasis with disruption of the concentrations of phosphorous, calcium and circulating hormones. With the improved survival brought about by modern management strategies, early recognition of the prognostic determinants is of paramount importance in improving the morbidity and quality of life of renal patients.

The aim of this review is to provide a skeletal perspective on the pathogenesis, radiological appearances, complications and principles of management of patients with chronic kidney disease.

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Published

2017-09-06

Issue

Section

Metabolic